Title |
Functionalization of Fe3O4 magnetic nanoparticles |
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Author |
Guihuan DU1, Zuli LIU1,*, Xing XIA1, Lihui JIA1, Qian CHU2, Suming ZHANG2 |
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Institute
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1. Department of Physics, Huazhong University of Science and Technology (HUST), Wuhan 430074, P.R.China;
2. Tongji Hospital, Huazhong University of Science and Technology (HUST), Wuhan 430070, P.R.China |
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Keywords: |
magnetic nanoparticles, modify, superparamagnetism, functionalization. |
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| Abstract | Chemical reaction was adopted to modify surface of dextran-SPION with functional groups in this study. Fourier Transform Infrared Spectrometer (FTIR) and X-ray Photoelectron Spectroscopy (XPS) were used to verify the functional groups of the modified dextran-SPION. The morphology and magnetic property of samples were studied by Transmission Electron Microscopy (TEM) and Vibrating Sample Magnetometer (VSM). Bioconjugation was studied by connecting samples with IgG FITC-antibody. The results indicate that the unmodified and modified dextran-SPION were superparamagnetic and about 5 nm in size. The modified dextran-SPION were found have good bioconjugation. |
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